N10-N16: Renal tubulo-interstitial diseases

Renal tubulo-interstitial diseases refer to an array of medical conditions that affect the tubular and interstitial areas of the kidneys. These issues typically result from a variety of causes, including infection, use of certain medications, autoimmune diseases, and genetic disorders. Initially, these conditions may present with non-specific symptoms such as fatigue, poor concentration, or subtle changes in urine output. As the disease progresses, more noticeable signs like frequent urination, swelling in the body, high blood pressure, and gradually declining kidney function become evident. Ultimately, these diseases can lead to chronic kidney disease or kidney failure. This spectrum also includes pyelonephritis—an inflammation of the kidney tissue, calyces, and pelvis—mostly caused by bacterial infection, and may lead to kidney scarring and impaired function. It's essential to mention that renal tubulo-interstitial diseases are not contagious and cannot be passed from one person to another.