N10-N16: Renal tubulo-interstitial diseases

N14: Drug- and heavy-metal-induced tubulo-interstitial and tubular conditions

The conditions in the N14 group refer to damages to the kidneys, specifically the parts known as the tubules and interstitium, which are caused by drugs or exposure to heavy metals. These pollutants can enter the body through contaminated food, water, air, or direct skin contact. Symptoms typically involve issues with kidney function, which may include changes in the frequency and color of urine, lower back pain, high blood pressure, and swelling in the body, particularly in the hands, feet and ankles. Over time, these conditions can progress and lead to chronic kidney disease. The drug- and heavy-metal-induced damages particularly affect the body's ability to filter the blood and remove waste products, which is the primary function of the kidneys. Early detection, usually through blood and urine tests, can slow the progression and limit the damage to the kidneys.