M30-M36: Systemic connective tissue disorders

M35: Other systemic involvement of connective tissue

Conditions classified under the ICD-10 code range M35 involve systemic issues in the body's connective tissue. Connective tissue is found throughout the body and holds our organs and tissues in place. These conditions are often autoimmune in nature, meaning the body's immune system mistakenly attacks its own cells. Symptoms vary widely depending on the specific condition and the areas of the body affected, but they often include fatigue, pain, and inflammation in the affected tissues or organs. These disorders can progress gradually or rapidly and may affect multiple body systems, including skin, joints, kidneys, lungs, heart, and eyes. The causes of these conditions are usually unknown, but they can be influenced by a combination of genetic, environmental, and hormonal factors. Some of these conditions are more common in women and may occur at any age, although they are more frequent in middle-aged people.