M35: Other systemic involvement of connective tissue

M35.0: Sicca syndrome [Sjögren]

With Sjögren’s syndrome, certain glands produce too little fluid. A gland is a tissue which produces a specific fluid or messenger substances. The salivary glands, for example, have this kind of tissue, but it is also in other organs.

With Sjögren’s syndrome, the body’s own immune system targets certain glands. The immune system protects the body from pathogens and foreign substances. The immune system can also destroy cells in the body that have pathologically changed. When the immune system targets certain glands, the glands involved can get damaged. The lachrymal glands and the salivary glands, for example, can get damaged. The lacrimal glands and salivary glands then produce too little fluid. As a result, one can have dry eyes and a dry mouth.

Other glands in the body that produce fluids may also be affected. As a result, one may have problems in the gastrointestinal area, for example.

With Sjögren’s syndrome, the immune system can also target muscles and joints. One can then have painful muscles and joints.