Y40-Y59: Drugs, medicaments and biological substances causing adverse effects in therapeutic use

Y45: Analgesics, antipyretics and anti-inflammatory drugs

The Y45 group of conditions refers to adverse effects involving analgesics, antipyretics, and anti-inflammatory drugs. These types of drugs are used in managing pain, reducing fever, and lessening inflammation in the body. Their use, however, can sometimes lead to unwanted side effects which can manifest in numerous ways. These may include gastrointestinal issues like nausea, vomiting or ulcers with the possibility of perforation and bleeding. These complications may escalate if the drugs are used for an extended period of time, or if they are not properly managed. Systemic reactions may also occur, affecting various bodily functions such as the kidneys or the cardiovascular system. In rare instances, these drugs can also result in severe allergic reactions. Symptoms, disease progression, and affected systems can largely vary depending on the specific drug and the individual's health status.