Q73: Reduction defects of unspecified limb

Reduction defects of unspecified limbs refer to a group of medical conditions where a part of a limb or a whole limb fails to form properly during embryonic development. These are congenital disorders, meaning they are present at birth. Such defects occur when the cells that make up the limb fail to grow or develop, or when they die off too soon. While the precise cause is often unknown, some factors have been associated with an increased risk, including maternal exposure to certain medications or chemicals, maternal illnesses, and genetic factors. Symptoms typically involve physical deformities that are visually noticeable, such as the absence of a limb or part of a limb. Additionally, these defects may impact the child's functionality, mobility, and ability to perform daily life activities. Each individual's disease progression varies, depending on the severity and location of the defect, alongside other potential health conditions. These defects primarily affect the musculoskeletal system.