N13: Obstructive and reflux uropathy

N13.6: Pyonephrosis

Pyonephrosis is a severe urinary tract condition that involves the accumulation of pus in the hollow part of the kidney, known as the renal pelvis. This typically occurs when an infection in the urinary tract goes untreated, leading to the build-up of infected material within the kidney. Common symptoms of pyonephrosis include back or side pain, an increased urge to urinate, frequent urination, fever, and sometimes blood in the urine. This condition can be quite serious, as it can disrupt the normal function of the kidney and potentially lead to kidney damage or failure if not addressed promptly. Additionally, because pyonephrosis is generally a result of an infection, it can result in the spread of bacteria into the blood (sepsis), which is a potentially life-threatening complication. The disease progression of pyonephrosis usually involves a gradual worsening of symptoms over time. However, the rate at which it progresses can depend on various factors, including the severity of the initial infection and the patient's overall health status.