M83: Adult osteomalacia

Adult osteomalacia is a group of conditions that causes soft and weak bones in adults due to a depletion of mineralization. The body needs minerals, like calcium and phosphate, to keep bones healthy. However, in osteomalacia, there is a shortage of these, typically due to a vitamin D deficiency. Causes include insufficient exposure to sunlight, certain medications, and certain medical conditions such as chronic kidney disease. The deficit of vitamin D leads to the inability of the body to absorb calcium effectively, resulting in softer bones. Common symptoms of this disorder include bone pain, muscular weakness, and a greater risk of fractures. The progression of the disease can lead to severe bone deformities if left untreated. This condition primarily affects the skeletal system, with the most severe impacts often found in the pelvis, lower back, hips, and legs.