L51: Erythema multiforme

Erythema multiforme is a skin condition that involves a rash and usually accompanies an infection or an immune response to a medication. The rash often looks like targets with a dark red or blue center, surrounded by a lighter red ring, and is usually symmetrical. It commonly appears on the hands, forearms, feet, and legs, though it can also develop on the face and upper body. Other accompanying symptoms can include fever, general discomfort, itching, joint aches, and an overall feeling of being unwell. The exact cause of erythema multiforme isn't known, but it's often linked to infections such as herpes simplex or to medications such as sulfonamides and antiseizure drugs. Most people with this condition recover within six weeks without treatment, though in severe cases it can lead to life-threatening complications, so immediate medical attention is necessary.