I25: Chronic ischaemic heart disease

I25.1: Atherosclerotic heart disease

Atherosclerotic heart disease, often referred to as coronary artery disease, is a condition where the arteries that supply blood to the heart become hardened and narrowed, restricting the flow of blood. This narrowing is primarily caused by a buildup of cholesterol, fat, and other substances on the inner walls of the arteries, forming a hard substance known as plaque. As the plaque builds up, it leads to inflammation and can decrease or block blood flow to the heart, causing chest pain, shortness of breath or, in more severe cases, a heart attack. This process is often slow and gradual, occurring over many years, and it is a leading cause of heart disease worldwide. Risk factors for atherosclerotic heart disease include advanced age, smoking, high blood pressure, high cholesterol levels, diabetes, obesity and a sedentary lifestyle.