E70-E90: Metabolic disorders

E84: Cystic fibrosis

Cystic fibrosis is a complex, genetic disease that primarily impacts the lungs and the digestive system. In patients with cystic fibrosis, the body creates thick and sticky mucus that accumulates in the lungs, making it hard to breathe and leading to severe lung infections. This mucus can also interfere with digestive processes as it obstructs the pancreas and stops natural enzymes from breaking down and absorbing food. The disease usually manifests in early childhood. Common symptoms include persistent coughing, frequent lung infections, wheezing or shortness of breath, poor growth or weight gain despite a good appetite, and frequent greasy or bulky stools. Over time, complications may affect other organ systems. The disease progresses differently in each individual and the symptoms can vary in severity. It is inherited, meaning it is caused by defective genes passed from parents to their children.