E70-E90: Metabolic disorders

E75: Disorders of sphingolipid metabolism and other lipid storage disorders

Disorders of sphingolipid metabolism and other lipid storage disorders, as the name suggests, are a group of conditions affecting how your body processes certain fats, known as sphingolipids and lipids. Interestingly, these fats are a normal part of cell structure within the body. When these are broken down in the body, as they should, everything runs smoothly. However, when they aren't processed correctly, they can build up in cells, often leading to harmful consequences. These disorders often occur due to problems with particular genes, passed down from parents to their children. Symptoms can vary widely, from brain issues like clumsiness or a decline in thinking skills, to physical problems, such as fatigue or weakness. Even the severity and progression of these disorders can differ widely among patients. The nervous system, bodily organs, and other body systems are commonly affected in these disorders.