Y54: Agents primarily affecting water-balance and mineral and uric acid metabolism

Y54.1: Mineralocorticoid antagonists [aldosterone antagonists]

Mineralocorticoid antagonists, also known as aldosterone antagonists, are a class of medications that counteract the effects of certain types of hormones in the body called mineralocorticoids, the most important of which is aldosterone. Aldosterone plays a critical role in maintaining blood pressure and electrolyte balance in the body. When excessive amounts of aldosterone are produced, it can lead to conditions such as high blood pressure (hypertension), heart failure, and certain types of kidney diseases. Use of mineralocorticoid antagonists can therefore help manage these health concerns. Side effects from taking these drugs may include high levels of potassium in the blood (hyperkalemia), changes in urination, or stomach upset. It's important to note that these drugs only manage symptoms and do not cure the underlying conditions.