Y53: Agents primarily affecting the gastrointestinal system

Y53.0: Histamine H 2 -receptor antagonists

Histamine H2-receptor antagonists refer to a group of drugs that are typically used to treat conditions related to excessive stomach acid. This group of drugs works by blocking the action of histamine, a chemical in the body that stimulates the production of stomach acid, on the H2 receptors in the stomach lining. Therefore, these antagonists effectively reduce the secretion of stomach acid. Common conditions that might necessitate the use of these drugs include gastroesophageal reflux disease (GERD), peptic ulcers, and Zollinger-Ellison syndrome. It's important to note that while these medications are effective in managing symptoms, they don't directly treat the underlying diseases like ulcers or GERD.