Y46: Antiepileptics and antiparkinsonism drugs

Y46.5: Valproic acid

Valproic acid is a medication often prescribed for the treatment of seizures in patients with epilepsy, bipolar disorder, and for the prevention of migraines. However, despite its benefits, exposure to this drug could lead to certain adverse effects known as Valproic Acid Toxicity. It can occur at any age but is more common in individuals who have liver disease, genetic metabolic disorders, or those who take high dose of the drug. Symptoms can range from mild, such as dizziness, weakness and stomach pain, to severe, including confusion, difficulty speaking and walking, and even loss of consciousness. This condition is classified under poisoning, toxicity, and adverse effects in the WHO ICD-10 classification. Left untreated, it can lead to potentially serious health complications. It is therefore crucial to manage doses effectively and monitor for any signs of toxicity while on this medication.