Y44: Agents primarily affecting blood constituents

Y44.1: Vitamin B 12 , folic acid and other anti-megaloblastic-anaemia preparations

Vitamin B12, folic acid, and other anti-megaloblastic-anaemia preparations pertain to medications used in the treatment of certain types of anemia, namely megaloblastic anemia. This form of anemia is characterized by the presence of unusually large, abnormal red blood cells, called megaloblasts, in the bone marrow. It usually results from the body's inability to absorb necessary nutrients, such as folic acid and vitamin B12. Initial symptoms may include fatigue, loss of appetite, and pale skin, and may progress to include weakness, difficulty concentrating, and irritability. This condition can have effects on several body systems, manifesting in the digestive and nervous systems, like a glossitis (inflamed tongue), digestive issues like diarrhoea or constipation, and neurologic conditions like dementia, depression, or memory loss, in severe unchecked deficiencies. These medications work to replenish the body's levels of these vital nutrients, helping to restore normal red blood cell size and function.