U84.3: Resistance to tuberculostatic drug(s)

Resistance to tuberculostatic drugs, coded as U84.3, is a serious health condition, involving the failure of specific medical drugs to successfully manage and treat tuberculosis, a bacterial infection primarily affecting the lungs. This resistance arises when the tuberculosis bacteria in the body become impervious to one or more tuberculostatic medications designed to eliminate them. Often, this drug resistance develops because of inappropriate or incomplete treatment, such as failing to complete a full course of medication. Individuals with drug-resistant tuberculosis can experience ongoing symptoms similar to general tuberculosis, which may include a persistent cough, fever, night sweats, and unintended weight loss. Over time, the resistance can lead to a progressive worsening of the disease, potentially damaging the respiratory system and other parts of the body. It also makes the condition more difficult to manage, potentially requiring stronger, less conventional treatments.