U82: Resistance to betalactam antibiotics

U82.2: Extended spectrum betalactamase (ESBL) resistance

Extended-spectrum beta-lactamase (ESBL) resistance is a condition where certain bacteria, often dwelling in the intestines, develop resistance to a group of antibiotics known as beta-lactam antibiotics. This includes antibiotics such as penicillin and cephalosporins. The resistance specifically means these antibiotics are no longer effective in treating infections caused by these bacteria. The bacteria form enzymes, termed 'extended-spectrum beta-lactamases,' which have the capability to disrupt these antibiotics. ESBL-producing bacterial infections can occur in any part of the body, but are most common in the urinary tract. Symptoms often depend on where the infection is, but may include fever, chills, swelling or redness, and pain in the affected area. These bacteria are typically spread through contaminated hands, surfaces, or medical devices, and can severely complicate treatment options when an infection occurs.