T86: Failure and rejection of transplanted organs and tissues

T86.8: Failure and rejection of other transplanted organs and tissues

Failure and rejection of other transplanted organs and tissues is a medical condition that occurs when the recipient's body sees the transplanted organ or tissue as foreign and initiates an immune response against it. This immune response can lead to damage or failure of the transplanted organ or tissue. Symptoms may vary greatly depending on the organ affected and the severity of the rejection. General symptoms can include pain, fever, and decline in the function of the transplanted organ or tissue. For example, for a transplanted kidney, symptoms may include reduced urine output and swelling in the legs. The condition can progress rapidly in some instances, further deteriorating the function of the transplanted organ or tissue, and can affect various body systems depending on the transplanted material. The exact cause of rejection is complex and involves a mix of genetic, immunologic, and environmental factors.