R77: Other abnormalities of plasma proteins

R77.8: Other specified abnormalities of plasma proteins

R77.8 refers to conditions characterized as 'other specified abnormalities of plasma proteins.' Plasma proteins are substances in your blood that serve several essential functions, including clotting blood, fighting diseases, and maintaining the right balance of fluid within your body. A deviation in these proteins, whether it be a deficiency or an excess, can lead to a variety of health issues. For instance, an increase in certain proteins could thicken the blood, resulting in clots, while a decrease could inhibit your body's ability to ward off infection. Symptoms of such abnormalities can vary significantly depending on the specific proteins affected and may include fatigue, frequent infections, unexplained weight loss, or issues with blood clotting (such as excessive bleeding or clotting). Abnormalities like these often occur as a result of other underlying conditions, such as liver disease or malignancies, so if such symptoms are present, further investigation may be needed to pinpoint the exact cause.