R65: Systemic Inflammatory Response Syndrome [SIRS]

R65.3: Systemic Inflammatory Response Syndrome of non-infectious origin with organ failure

Systemic Inflammatory Response Syndrome (SIRS) of non-infectious origin with organ failure is a serious medical condition. It occurs when the body's normal response to something wrong gets out of control, resulting in an exaggerated inflammation. Although the title suggests an infection isn't present, the cause can be due to non-infectious reasons such as severe injury, trauma, or medical conditions like pancreatitis. This overactive response often affects the whole body and can lead to problems in different organs, like the heart, kidneys, or lungs. When the response is so severe that it leads to organ failure, the situation becomes critical. Common symptoms may include fever, increased heart rate, rapid breathing, and abnormal blood tests. The condition can progress quickly, leading to severe organ damage and life-threatening circumstances. This condition requires immediate medical intervention, typically within a specialized intensive care unit.