R45: Symptoms and signs involving emotional state

R45.1: Restlessness and agitation

Restlessness and agitation, classified under the ICD-10 code R45.1, refer to a spectrum of symptoms encompassing a range of both physical and psychological responses. Restlessness is described as the feeling of being unable to sit still or a sense of unease that provokes involuntary movement or activity. Agitation is typically characterized by increased tension, restlessness, and a profound sense of discomfort, often accompanied by a disproportionate reaction to stimuli that are generally well-tolerated by most individuals. These symptoms may be triggered by various factors including mental health disorders, neurological conditions, physiological imbalances or stressful situations. Restlessness and agitation are not diseases in themselves but indicative of underlying issues, requiring further medical evaluation to pinpoint the root cause.