R20-R23: Symptoms and signs involving the skin and subcutaneous tissue

R22: Localized swelling, mass and lump of skin and subcutaneous tissue

Localized swelling, mass, and lump of the skin and subcutaneous tissue, classified under ICD-10 code R22, refer to common physical manifestations visible on the skin surface. Subcutaneous tissue is a layer of fat and connective tissue that houses larger blood vessels and nerves. These conditions present as observable and palpable enlargements or irregularities on or beneath the skin. They are typically non-moving, meaning they hold their position when the skin is slightly stretched or compressed. Causes can be various and include inflammation, infection, cysts, benign or malignant tumors, or trauma to the area. Symptoms generally depend on the location and size of the mass. Larger ones may cause discomfort or pain, especially if they press against nerves or limit mobility. These conditions generally do not transmit from person to person. While some may remain the same size, others may grow or shrink over time. The progression and potential complications largely depend on the underlying cause.