R10-R19: Symptoms and signs involving the digestive system and abdomen

R17: Hyperbilirubinaemia, with or without jaundice, not elsewhere classified

Hyperbilirubinaemia, with or without jaundice, not elsewhere classified, refers to a group of conditions characterized by elevated levels of bilirubin in the bloodstream. Bilirubin is a yellow substance the body creates when it replaces old red blood cells. The liver helps to break down bilirubin so that it can be removed from the body. However, if the liver is damaged or the bilirubin production is too much for the liver to handle, it builds up in the body. This build-up can lead to yellowing of the skin and eyes, a condition known as jaundice. However, hyperbilirubinaemia can occur without visible signs of jaundice. Symptoms of these conditions can include fatigue, abdominal pain, weight loss, and dark urine. These conditions primarily affect the liver and circulatory system and may progress slowly or rapidly based on the underlying cause. Common causes include certain genetic diseases, liver diseases, or conditions that accelerate the breakdown of red blood cells.