R16: Hepatomegaly and splenomegaly, not elsewhere classified

Hepatomegaly and splenomegaly refer to a group of conditions where the liver (hepatomegaly) and the spleen (splenomegaly) are enlarged beyond their normal sizes, respectively. They can occur separately or together, and are not specific diseases, but rather symptoms that occur due to underlying various conditions. Common causes include liver diseases such as cirrhosis or hepatitis, blood disorders such as leukemia, infections such as mononucleosis, or heart failure. Hepatomegaly might present with feelings of fullness or abdominal pain, while splenomegaly might cause pain or fullness in the left upper abdomen that may spread to the left shoulder. They are usually detected during a physical examination and can be confirmed by an ultrasound or CT scan. The progression depends on the underlying cause; some can be mild and temporary while others can be severe and chronic. They primarily affect the digestive and circulatory systems.