Q80: Congenital ichthyosis

Q80.1: X-linked ichthyosis

The top of layer of skin is made up of skin cells that are keratinized. These skin cells are initially in one of the lower skin layers. When the skin cells migrate upwards toward the skin’s surface, they keratinize, forming a solid layer.

The genetic information in your cells has changed. This disrupts the keratinization of your skin.

This condition causes the skin to be dry, rough and flaky. The scales may appear gray. It can also affect the skin all over the body. The insides of the joints can remain free of changes.

Certain forms of the condition can also produce other symptoms. The symptoms can also affect other parts of the body.

This disease is hereditary. Other family members may also be affected. Boys and men are particularly affected.