Q80: Congenital ichthyosis

Q80.0: Ichthyosis vulgaris

The top of layer of skin is made up of skin cells that are keratinized. These skin cells are initially in one of the lower skin layers. When the skin cells migrate upwards toward the skin’s surface, they keratinize, forming a solid layer.

The genetic information in your cells has changed. This disrupts the keratinization of your skin.

This condition causes the skin to be dry, rough and flaky. The front of the legs and the backs of the arms are often particularly affected. However, the skin all over the body can also be affected. The insides of the joints can remain free of changes. The skin on the palms and soles of the feet can also be thickened. The grooves in the palms can then be more visible than usual. The symptoms can improve or completely disappear in heat or high humidity.

Certain forms of the condition can also produce other symptoms. The symptoms can also affect other parts of the body.

This disease is hereditary. Other family members may also be affected.