Q21: Congenital malformations of cardiac septa

Q21.0: Ventricular septal defect

The heart pumps blood through the body. Inside the heart are 4 chambers. There are 2 heart atria and 2 ventricles. Both heart atria and both ventricles are separated from each other by a partition.

A hole in the cardiac septum may develop during development in the womb before birth. The cardiac septum sometimes fails to close up as normal during development. A hole in the cardiac septum can result in blood flowing back and forth directly between the upper chambers (atria) or lower chambers (ventricles). This usually results in a change to normal blood flow. In some cases, this means that the heart and lungs are placed under greater strain. The blood supply to the body may also be impacted due to a hole in the cardiac septum.

You have a hole in the cardiac septum, the wall that separates the left and right sides of your heart. This causes blood to flow back from the left lower chamber (ventricle) directly into the right ventricle because the blood pressure in the left heart is normally higher than in the right heart. Blood flows back from the right heart through the lungs. The additional blood flow puts the heart and lungs under greater strain than normal. You may have various symptoms as a result. As a result, the heart may no longer be able to pump blood adequately through the body. This may cause you to sweat and be short of breath. In addition, the body sometimes stops growing normally.

The bigger the hole in the cardiac septum between the ventricles, the sooner symptoms will develop. Often, the symptoms are also more severe with a larger hole. Having only a small hole in the septum may mean that you don’t have any symptoms at all.