N17: Acute renal failure

N17.2: Acute renal failure with medullary necrosis

Acute renal failure with medullary necrosis, also known as tubular necrosis, is a severe kidney condition that occurs suddenly. This disease typically arises when there's an injury to the internal part of the kidney. Specifically, the medulla of the kidney, which includes structures critical for the kidney to perform its filtering function, undergoes tissue death or necrosis. Common signs of this disease include reduced urine output, making less than 400 milliliters of urine in a day (oliguria), or not making urine at all (anuria). Additionally, patients may experience fatigue, swellings in legs, ankles, and around the eyes, shortness of breath, confusion, seizures, or even coma due to the build-up of waste products in the body. This condition can distort the usual functions of the kidney, leading to an accumulation of waste products, electrolyte imbalance, and alterations in body fluid balance, which can be life-threatening if not promptly managed.