M89: Other disorders of bone

M89.5: Osteolysis

Osteolysis is a specific medical condition that refers to the process of bone loss, or the dissolving of bone tissue. It is characterized primarily by excessive resorption of bone due to the activity of osteoclasts, the cells responsible for the degradation of bone material. Several triggers can initiate osteolysis, including trauma, infection, autoimmune diseases, and certain medications. Individuals with osteolysis may experience a wide range of symptoms depending on the extent and location of bone loss. These could include pain, swelling, limited range of motion, and potentially instability in the affected region. Over time, if left unaddressed, osteolysis can lead to significant bone weakening and cause fractures, deformity, or even loss of function in severe instances. It can affect any bone in the body and is diagnosed using imaging tests such as X-rays, CT scans, or MRI.