M72: Fibroblastic disorders

M72.0: Palmar fascial fibromatosis [Dupuytren]

With Dupuytren’s disease, the connective tissue in the inner surface of the hand hardens and contracts. Over time the connective tissue can increasingly harden and contract.

In the palm of the hand there is tough connective tissue that, for instance, protects the nerves and blood vessels in the hand. Between this connective tissue tendons run from muscles. These muscles are what moves the fingers.

When the connective tissue hardens and contracts, moving your fingers may become harder than usual. At some point you may no longer be able to extend your fingers fully. Dupuytren’s disease may also damage the nerves or blood vessels in the hand. There may then be some pain.

The precise cause of Dupuytren’s disease is not yet known.