M30-M36: Systemic connective tissue disorders

M32: Systemic lupus erythematosus

Systemic lupus erythematosus (SLE) is a complex, chronic autoimmune disease that affects multiple systems in the body. In SLE, the immune system mistakenly attacks healthy tissues, creating widespread inflammation and damage. The cause of SLE is currently unknown, however, it's believed to be a combination of genetic, environmental, and hormonal factors. Its ability to mimic other diseases makes it challenging to diagnose. Symptoms vary among individuals and may change over time, but can include skin rashes, joint pain, fatigue, and kidney problems. The condition has periods of illness, called flares, and periods of wellness, or remission. It primarily affects women of childbearing age but can occur at any age, in either sex, and in all races and ethnic groups. Disease progression differs from person to person, with some experiencing mild symptoms and others experiencing serious complications. It's not contagious and can't be transmitted from person to person.