M11: Other crystal arthropathies

M11.0: Hydroxyapatite deposition disease

Hydroxyapatite deposition disease, or simply HADD, is a medical condition characterized by the abnormal deposition of hydroxyapatite – a calcium-rich crystalline compound – in any joint. The deposition can occur in the tendons, ligaments, or joint spaces, particularly around the shoulders, knees, or wrists. Often starting without any clear cause, this illness can lead to pain, inflammation, and the formation of masses or nodules. The severity of HADD might vary: sometimes it remains asymptomatic while in other cases it could lead to significant joint discomfort or even cause damage to surrounding tissues. Over time, this deposit can cause the body to react, leading to an inflammatory response, which in turn can result in symptoms like redness, swelling, and warmth around the affected joint. The progression of the disease is typically slow and steady. Due to the buildup of hydroxyapatite crystals in or around joints, the patient's mobility can also be affected.