M05: Seropositive rheumatoid arthritis

M05.8: Other seropositive rheumatoid arthritis

Seropositive rheumatoid arthritis is a chronic autoimmune condition in which your body mistakenly attacks its own tissues, particularly the lining of your joints, causing inflammation, swelling, and pain. This type, "other seropositive," means that blood tests show the presence of specific antibodies, known as rheumatoid factor or anti-citrullinated protein antibodies, which are usually associated with more severe symptoms compared to seronegative rheumatoid arthritis. Common symptoms can range from joint pain and swelling, stiffness particularly in the morning, to general body symptoms like fatigue and low-grade fever. Over time, the condition can cause joint deformities and disability due to damage of joint tissues. Although it primarily affects the joints, in severe cases it can also affect other systems in the body like the heart, lungs and even skin. It is still not completely understood why some people develop these antibodies and others do not, but it's likely a combination of genetics and environmental factors.