E80: Disorders of porphyrin and bilirubin metabolism

E80.4: Gilbert syndrome

When old blood cells are broken down, bile pigments come into being. These bilirubins are modified by a protein in the liver.

You have less of this protein. This condition is congenital, which means you were born with it. If the protein is not working properly, bile pigments will accumulate in the body. The less you have of this protein, the more bile pigments accumulate. That is especially the case when the liver has to do a lot of work. The liver has to work a lot when you drink alcohol or when you have contact with pathogens. Your eyes or skin sometimes appear yellow as a result.

The disease is usually harmless and does not have to be treated.