D89: Other disorders involving the immune mechanism, not elsewhere classified

D89.3: Immune reconstitution syndrome

Immune reconstitution syndrome is a condition that occurs in some people who are receiving treatment for diseases such as HIV/AIDS or cancer. This syndrome happens when the immune system, which has been weakened, starts to recover, but then reacts too strongly against the pathogens (like bacteria, viruses, or fungi) that remained in the body while the immune system was weak. Common symptoms can include fever and inflammation in many different parts of the body, including the skin, eyes, lungs, or stomach. This syndrome can affect various systems in the body and can sometimes cause severe problems. The progression of the disease varies from person to person and depends on the type and stage of the initial illness as well as the strength of the immune response.