D80-D89: Certain disorders involving the immune mechanism

D83: Common variable immunodeficiency

Common Variable Immunodeficiency (CVID) represents a group of disorders that hamper the immune system and make it difficult to fight off infections. These conditions usually involve two parts of your immune system, known as B cells and T cells, which generally have trouble functioning properly. As a result, people with CVID often experience frequent and prolonged bacterial infections, particularly in the lungs, sinuses, and ears. Other symptoms could include chronic diarrhea and weight loss due to inflammation in the gastrointestinal tract. The conditions usually develop gradually and can appear at any age, affecting both men and women. The origins of CVID are generally genetic and can be passed down through families. However, many cases appear without any clear family links. It's important to note that the disease progression can vary widely, with some individuals living nearly symptom-free while others endure severe, recurring infections.