D70-D77: Other diseases of blood and blood-forming organs

D70: Agranulocytosis

Agranulocytosis refers to a group of conditions characterized by a severely decreased number of white blood cells called neutrophils, which play a significant role in the body's defense against infections. This condition can be caused by various factors, including certain medications, chemotherapy, radiation therapy, autoimmune diseases, and bone marrow disorders. The lowered neutrophil counts make individuals susceptible to bacterial and fungal infections. Symptoms often resemble those of an infection and may include fever, chills, and sore throat, among others. In severe cases, if left untreated, it may progress to involve multiple body systems and may also lead to life-threatening infections. Therefore, the condition should be recognized and managed promptly.