D68: Other coagulation defects
D68.3: Haemorrhagic disorder due to circulating anticoagulants
Haemorrhagic disorder due to circulating anticoagulants, also known as acquired haemophilia, is a rare bleeding disorder. It occurs when the body mistakenly begins to produce antibodies (circulating anticoagulants) which attack and neutralize some of its own clotting proteins, primarily Factor VIII, responsible for normal blood clotting. The presence of these anticoagulants in the bloodstream leads to difficulties in blood clotting. As the name implies, this disorder is characterized by uncontrolled and often spontaneous bleeding. The typical symptoms include bruising, nosebleeds, bleeding gums, blood in urine or stool, heavy periods in women, and in severe cases, spontaneous internal bleeding which may be life-threatening. The disorder can occur in anyone irrespective of age or sex, but it is more common among the elderly and in postpartum women.
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