D60: Acquired pure red cell aplasia [erythroblastopenia]

Acquired pure red cell aplasia, also known as erythroblastopenia, is a rare condition in which the body stops producing red blood cells, leading to anemia. While it can affect people of all ages, it occurs more frequently in adults. It is termed 'acquired' because it is not present from birth but develops later, often from unknown causes, though it can sometimes stem from medications, autoimmune disorders, or viral infections. The lack of red blood cells results in fatigue, weakness, and shortness of breath, due to the decreased oxygen supply to the body's cells. The condition's progression may vary and depends on the underlying cause; while some individuals may experience a slow progression, in others it can be sudden. As it affects the body's blood-making system, it can also cause pale or yellowish skin and cold hands or feet. The condition is diagnosed through blood tests and bone marrow examinations.