D55-D59: Haemolytic anaemias

D58: Other hereditary haemolytic anaemias

Other hereditary haemolytic anaemias are a group of blood disorders where the body destroys red blood cells faster than it can make them, due to inherited problems. These conditions generally arise due to genetic mutations which may affect several aspects of the red blood cell, leading to premature breakdown. Common symptoms include feeling weak or tired, jaundice (yellowing of the skin and eyes), an enlarged spleen, and dark urine. The speed at which these conditions progress and their severity can vary widely, depending largely on the specific genetic mutation causing the anaemia. These disorders primarily affect the body's haematological (blood) system, but can sometimes also impact other systems due to the low level of circulating red blood cells. These conditions are usually present from birth, and tend to persist throughout the person's life.