D47.5: Chronic eosinophilic leukaemia [hypereosinophilic syndrome]
Chronic eosinophilic leukaemia, also known as hypereosinophilic syndrome, is a rare and complex blood disorder. It involves the overproduction of eosinophils, a type of white blood cell, in the bone marrow. This leads to a high concentration of eosinophils in the bloodstream, which can infiltrate and damage multiple organs in the body including the heart, lungs, liver, and skin. Typical symptoms include fatigue, fever, cough, rash, and abdominal pain. Uncontrolled disease progression may induce severe complications, including heart disease, lung disease, and even organ failure. Despite presenting mostly in adult males, it can affect people of all ages and genders. The cause of this condition is usually unknown, but it could potentially be triggered by certain genetic mutations, allergies, infections, or exposure to certain medications or toxins.
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