Osteomyelofibrosis, also known as primary myelofibrosis, is a rare type of bone marrow disorder that disrupts your body's normal production of blood cells. It occurs when there's an excessive growth of fibrous tissues within the bone marrow, leading to a reduction in the production of red and white blood cells and platelets. This can result in a variety of symptoms, including anemia that leads to feelings of weakness or fatigue, bruising or bleeding easily due to a shortage of platelets, and an increased risk of infections because of a lack of white blood cells. Additionally, osteomyelofibrosis might also cause the liver and spleen to enlarge as these organs take over the blood production from the bone marrow. It's a progressive disease, meaning it tends to worsen over time. The exact cause of this condition is not entirely understood, but genetic mutations are often associated with its development.
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