C91: Lymphoid leukaemia

C91.6: Prolymphocytic leukaemia of T-cell type

Prolymphocytic leukaemia of T-cell type is a rare form of blood cancer that arises from the T cells, a type of white blood cell. This condition is characterized by a high number of prolymphocytes, immature white blood cells, circulating in the bloodstream. Symptoms present in an individual may vary and can include general lack of energy, unexplained weight loss, frequent infections, enlarged liver or spleen, and noticeable swelling of lymph nodes. It often affects individuals aged 65 and above, although it can develop at any age. The development of T-cell prolymphocytic leukaemia is not based on transmission from one person to another but arises from unknown genetic changes in the T cells. The specific cause of this condition remains largely unexplored. Over time, this can negatively impact the body's immune response and the production of healthy blood cells, leading to disease progression.