C81-C96: Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue

C81: Hodgkin lymphoma

Hodgkin lymphoma is a group of cancers that start from white blood cells, specifically lymphocytes, which are primary components of the body's immune system. This condition is characterized by the presence of a unique type of cell, known as the Reed-Sternberg cell. Lymphomas, including Hodgkin lymphoma, commonly initiate in lymph nodes, which are small, bean-shaped organs that produce and store cells that fight infection and diseases. The cause of Hodgkin lymphoma is not well understood, but it is thought to occur when an error in the DNA causes excessive growth and division of these cells. Some common signs and symptoms of Hodgkin lymphoma may include swollen lymph nodes, fatigue, unexplained weight loss, and severe night sweats. The progress of the disease varies greatly among individuals. It may advance from one group of lymph nodes to the next in an orderly manner or may spread randomly to other tissues and organs such as the spleen and liver. Much like other cancers, Hodgkin lymphoma can affect various body systems based on where it grows and how widespread it becomes.