C74: Malignant neoplasm of adrenal gland

Malignant neoplasms of the adrenal gland refer to a group of cancers that primarily originate from the adrenal glands, which are small hormone-producing organs located atop each kidney. These occupationally linked cancers grow abnormally and uncontrollably, often disrupting the adrenal glands' regular functioning and causing an overproduction or underproduction of certain hormones. In the early stages, one may not express any noticeable symptoms. However, as the cancer progresses, symptoms such as unexplained weight loss or gain, persistent pain in the back or side, and a noticeable lump in the abdomen may emerge. Malignant adrenal neoplasms can also lead to hypertension or hypotension, depending upon which hormones are affected. While the exact causes of malignant adrenal neoplasms remain unknown, a history of tobacco use, exposure to certain industrial chemicals, and certain inherited genetic disorders are considered potential risk factors.