C45-C49: Malignant neoplasms of mesothelial and soft tissue

C49: Malignant neoplasm of other connective and soft tissue

Malignant neoplasm of other connective and soft tissue is a group of cancers that begin in the body's connective or soft tissues, including muscles, tendons, fat, blood vessels, lymph vessels, nerves, and synovial tissues (tissues around joints). These types of cancers, while relatively rare, can occur almost anywhere in the body. They might not exhibit noticeable symptoms in the early stages, but as they progress, they can cause pain, swelling, or a noticeable lump. They might also interfere with normal function, depending on their location. Risk factors for these cancers can include exposure to certain chemicals or radiation and genetics. It is also possible, however rare, for these cancers to spread (metastasize) to other parts of the body. The disease trajectory varies widely, depending on the specific type of cancer within this group and how early it's detected.