C48: Malignant neoplasm of retroperitoneum and peritoneum

Malignant neoplasms of the retroperitoneum and peritoneum belong to a group of conditions characterized by the uncontrolled growth of harmful cells within the retroperitoneal or peritoneal spaces of the body. The retroperitoneum hosts key body structures like the kidneys, adrenal glands, pancreas, nerves, and large blood vessels, while the peritoneum is a thin tissue layer lining the abdominal cavity and covering the organs within it. These cancers develop when cells in these areas mutate and multiply at a faster rate than they should, forming a mass or tumor. A variety of factors can contribute to these harmful changes, including certain inherited genetic conditions, exposure to specific chemicals, and some chronic diseases. Typically, these cancers present nonspecific symptoms like abdominal pain, bloating, or unexplained weight loss, which can make them difficult to diagnose at an early stage. Over time, these malignant growths can spread to nearby organs or through the bloodstream to other parts of the body, impacting multiple bodily functions and systems.