C45-C49: Malignant neoplasms of mesothelial and soft tissue
C46: Kaposi sarcoma
Kaposi Sarcoma (KS) is an uncommon kind of cancer formed from cells that line the lymph or blood vessels. Generally, this condition manifests as abnormal skin growths that may appear red, purple, or brown. These lesions can also develop in other parts of the body such as the mouth, lymph nodes, or gastrointestinal tract. KS is caused by infection with the Human Herpesvirus-8 (HHV-8) and is seen more frequently in individuals with compromised immune systems, such as people living with HIV/AIDS. The disease course of KS varies, it might progress slowly for years or grow aggressively, depending on the individual's immune health. While skin symptoms are often the first to present, more severe symptoms can emerge as the disease progresses, such as lymphedema or respiratory symptoms, if related organs are involved.
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