C40: Malignant neoplasm of bone and articular cartilage of limbs

Malignant neoplasms of bone and articular cartilage of limbs are a group of cancers that originate in the bones or the connective tissues of joints in arms and legs. They can occur due to random mutations in the DNA of cells in these areas, leading to an uncontrolled growth of abnormal cells that form a tumor. Common symptoms may include pain in the affected area, swelling, and fractures. As the disease progresses, if left untreated, the cancer cells can invade nearby tissues or spread to other parts of the body through the bloodstream or lymphatic system, a condition known as metastasis. These conditions can affect anyone, but they are more common in children and young adults. Notably, these types of cancers are not typically caused by injuries, and it is very rare for them to be spread from person to person.